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研究案内

2016年(平成28年)業績一覧


婦人科腫瘍研究室周産期研究室生殖医学研究室

婦人科腫瘍研究室

英文原著論文

Murakami R, Matsumura N, Mandai M, Yoshihara K, Tanabe H, Nakai H, Yamanoi K, Abiko K, Yoshioka Y, Hamanishi J, Yamaguchi K, Baba T, Koshiyama M, Enomoto T, Okamoto A, Murphy SK, Mori S, Mikami Y, Minamiguchi S, Konishi I.
Establishment of a Novel Histopathological Classification of High-Grade Serous Ovarian Carcinoma Correlated with Prognostically Distinct Gene Expression Subtypes.
Am J Pathol. 2016 May;186(5):1103-13.

Yamanoi K, Matsumura N, Murphy SK, Baba T, Abiko K, Hamanishi J, Yamaguchi K, Koshiyama M, Konishi I, Mandai M.
Suppression of ABHD2, identified through a functional genomics screen, causes anoikis resistance, chemoresistance and poor prognosis in ovarian cancer.
Oncotarget. 2016 Jul 26;7(30):47620-47636.

Abou-Taleb H, Yamaguchi K, Matsumura N, Murakami R, Nakai H, Higasa K, Amano Y, Abiko K, Yoshioka Y, Hamanishi J, Koshiyama M, Baba T, Yamada R, Matsuda F, Konishi I, Mandai M.
Comprehensive assessment of the expression of the SWI/SNF complex defines two distinct prognostic subtypes of ovarian clear cell carcinoma.
Oncotarget. 2016 Aug 23;7(34):54758-54770.

Murakami R, Matsumura N, Brown JB, Wang Z, Yamaguchi K, Abiko K, Yoshioka Y, Hamanishi J, Baba T, Koshiyama M, Mandai M, Yamada R, Konishi I.
Prediction of taxane and platinum sensitivity in ovarian cancer based on gene expression profiles.
Gynecol Oncol. 2016 Apr;141(1):49-56.

Peng J, Yoshioka Y, Mandai M, Matsumura N, Baba T, Yamaguchi K, Hamanishi J, Kharma B, Murakami R, Abiko K, Murphy SK, Konishi I.
The BMP signaling pathway leads to enhanced proliferation in serous ovarian cancer-a potential therapeutic target.
Mol Carcinog. 2016 Apr;55(4):335-45.

Sakae C, Yamaguchi K, Matsumura N, Nakai H, Yoshioka Y, Kondoh E, Hamanishi J, Abiko K, Koshiyama M, Baba T, Kido A, Mandai M, Konishi I.
Groin lymph node detection and sentinel lymph node biopsy in vulvar cancer.
J Gynecol Oncol. 2016 Nov;27(6):e57.

Abou-Taleb HA, Koshiyama M, Matsumura N, Baba T, Yamaguchi K, Hamanishi J, Abiko K, Yamanoi K, Murakami R, Horikawa N, Taha AA, Kitamura S, Konishi I.
Clinical efficacy of neoadjuvant chemotherapy with irinotecan (CPT-11) and nedaplatin followed by radical hysterectomy for locally advanced cervical cancer.
J Int Med Res. 2016 Apr;44(2):346-56.

Hino M, Yamaguchi K, Abiko K, Yoshioka Y, Hamanishi J, Kondoh E, Koshiyama M, Baba T, Matsumura N, Minamiguchi S, Kido A, Konishi I.
Magnetic resonance imaging findings and prognosis of gastric-type mucinous adenocarcinoma (minimal deviation adenocarcinoma or adenoma malignum) of the uterine corpus: Two case reports.
Mol Clin Oncol. 2016 May;4(5):699-704.

Sakai M, Abiko K, Matsumura N, Kondoh E, Yamaguchi K, Minamiguchi S, Kurata Y, Kido A, Konishi I.
Two cases of Wolffian tumor with novel magnetic resonance imaging findings reflecting characteristic pathology.
J Obstet Gynaecol Res. 2016 Aug;42(8):1046-51.

Kitamura S, Matsumura N, Ohtake N, Kita M, Konishi I.
Tubo-ovarian abscess with endometrial cyst probably infected by Campylobacter fetus: Two cases.
J Obstet Gynaecol Res. 2016 Aug;42(8):1052-7.


英文総説

Hamanishi J, Mandai M, Konishi I.
Immune checkpoint inhibition in ovarian cancer.
Int Immunol. 2016 Jul;28(7):339-48. doi: 10.1093/intimm/dxw020. Epub 2016 Apr 7. Review.

Mandai M, Hamanishi J, Abiko K, Matsumura N, Baba T, Konishi I.
Dual Faces of IFNγ in Cancer Progression: A Role of PD-L1 Induction in the Determination of Pro- and Antitumor Immunity.
Clin Cancer Res. 2016 May 15;22(10):2329-34. doi: 10.1158/1078-0432.CCR-16-0224. Epub 2016 Mar 25.

Mandai M, Hamanishi J, Abiko K, Matsumura N, Baba T, Konishi I.
Anti-PD-L1/PD-1 immune therapies in ovarian cancer: basic mechanism and future clinical application.
Int J Clin Oncol. 2016 Jun;21(3):456-61. doi: 10.1007/s10147-016-0968-y. Epub 2016 Mar 11. Review.

Hamanishi J, Mandai M, Matsumura N, Abiko K, Baba T, Konishi I.
PD-1/PD-L1 blockade in cancer treatment: perspectives and issues.
Int J Clin Oncol. 2016 Jun;21(3):462-73. doi: 10.1007/s10147-016-0959-z. Epub 2016 Feb 22. Review.


和文原著論文

和文総説

学会発表

周産期研究室

生殖医学研究室

京都大学医学部附属病院 産科婦人科

〒606-8507 京都市左京区聖護院川原町54
京都大学大学院医学研究科 器官外科学講座
(婦人科学産科学)

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