研究業績


臨床をすべての中心として、ひとつひとつの症例を大切にしながら、日々研究に教育に勤しんでいます。その過程で、教室メンバーが関わってきた論文をご紹介します。

[2017]    [2016]

1. Eso Y, Uza N, Yamagishi H, Imada K, Kimura Y, Masui T, Kodama Y, Seno H.
Utility of KRAS mutational analysis in the preoperative diagnosis of synchronous pancreatic cancer and intrahepatic cholangiocarcinoma.
Medicine (Baltimore). 2017 Dec;96(50):e9217.
2. Handa T, Matsui S, Yoshifuji H, Kodama Y, Yamamoto H, Minamoto S, Waseda Y, Sato Y, Kubo K, Mimori T, Chiba T, Hirai T, Mishima M.
Serum soluble interleukin-2 receptor as a biomarker in immunoglobulin G4-related disease.
Mod Rheumatol. 2017 Dec 18:1-21.
3. Masui T, Takaori K, Anazawa T, Sato A, Nakano K, Uchida Y, Yogo A, Goto Y, Matsumoto S, Kodama Y, Kanai M, Isoda H, Mizumoto M, Kawaguchi Y, Shibuya K, Itasaka S, Uemoto S.
A Prospective Study of Intensity-modified Radiation Therapy in Comparison with Conventional 3D-RT for BR Pancreatic Cancer Patients with Arterial Involvement.
Anticancer Res. 2017 Dec;37(12):7023-7030.
4. Ueda Y, Kaido T, Okajima H, Hata K, Anazawa T, Yoshizawa A, Yagi S, Taura K, Masui T, Yamashiki N, Haga H, Nagao M, Marusawa H, Seno H, Uemoto S.
Long-term prognosis and recurrence of primary sclerosing cholangitis after liver transplantation: A single-center experience.
Transplant Direct. 2017 Nov 20;3(12):e334.
5. Matsumoto T, Takai A, Eso Y, Kinoshita K, Manabe T, Seno H, Chiba T, Marusawa H.
Proliferating EpCAM-positive ductal cells in the inflamed liver give rise to hepatocellular carcinoma.
Cancer Res. 2017 Nov 15;77(22):6131-6143.
6. Hiejima E, Yasumi T, Nakase H, Matsuura M, Honzawa Y, Higuchi H, Okafuji I, Yorifuji T, Tanaka T, Izawa K, Kawai T, Nishikomori R, Heike T.
Tricho-hepato-enteric syndrome with novel SKIV2L gene mutations: A case report.
Medicine (Baltimore). 2017 Nov;96(46):e8601.
7. Tsuji Y, Takahashi N, Isoda H, Koizumi K, Koyasu S, Sekimoto M, Imanaka Y, Yazumi S, Asada M, Nishikawa Y, Yamamoto H, Kikuchi O, Yoshida T, Inokuma T, Katsushima S, Esaka N, Okano A, Kawanami C, Kakiuchi N, Shiokawa M, Kodama Y, Moriyama I, Kajitani T, Kinoshita Y, Chiba T.
Early diagnosis of pancreatic necrosis based on perfusion CT to predict the severity of acute pancreatitis.
J Gastroenterol. 2017 Oct;52(10):1147-1148.
8. Nosaka T, Naito T, Hiramatsu K, Ohtani M, Nemoto T, Marusawa H, Ma N, Hiraku Y, Kawanishi S, Yamashita T, Kaneko S, Nakamoto Y.
Gene expression profiling of hepatocarcinogenesis in a mouse model of chronic hepatitis B.
PLoS One. 2017 Oct 2;12(10):e0185442.
9. Eso Y, Mishima M, Fukuda A.
An Unusual Cause of Hepatic Dysfunction.
Gastroenterology. 2017 Oct;153(4):906-907.
10. Ikeda A, Ikeda K, Takai A, Takahashi K, Ueda Y, Marusawa H, Seno H, Inagaki N, Kokuryu H.
Hepatitis C Treatment with Sofosbuvir and Ledipasvir Accompanied by Immediate Improvement in Hemoglobin A1c.
Digestion. 2017 Oct 30;96(4):228-230.
11. Eso Y, Takai A, Arasawa S, Ueda Y, Seno H.
Granulomatous hepatitis due to disseminated bacillus Calmette-Guerin disease.
Gastroenterol Hepatol. 2017 Sep;32(9):1538.
12. Xue P, Hang J, Huang W, Li S, Li N, Kodama Y, Matsumoto S, Takaori K, Zhu L, Kanai M.
Validation of Lymphocyte-to-Monocyte Ratio as a Prognostic Factor in Advanced Pancreatic Cancer: An East Asian Cohort Study of 2 Countries.
Pancreas. 2017 Sep;46(8):1011-1017.
13. Ishii T, Minaga K, Ogawa S, Ikenouchi M, Yoshikawa T, Akamatsu T, Seta T, Urai S, Uenoyama Y, Yamashita Y.
Effectiveness and safety of metallic stent for ileocecal obstructive colon cancer: a report of 4 cases.
Endosc Int Open. 2017 Sep;5(9):E834-E838.
14. Eso Y, Yoshiji S, Kodama Y, Seno H.
Skull metastasis from cholangiolocellular carcinoma.
Dig Liver Dis. 2017 Sep;49(9):1057.
15. Ueda Y, Ikegami T, Akamatsu N, Soyama A, Shinoda M, Goto R, Okajima H, Yoshizumi T, Taketomi A, Kitagawa Y, Eguchi S, Kokudo N, Uemoto S, Maehara Y.
Treatment with sofosbuvir and ledipasvir without ribavirin for 12 weeks is highly effective for recurrent hepatitis C virus genotype 1b infection after living donor liver transplantation: a Japanese multicenter experience.
J Gastroenterol. 2017 Aug;52(8):986-991.
16. Hijioka S, Hosoda W, Matsuo K, Ueno M, Furukawa M, Yoshitomi H, Kobayashi N, Ikeda M, Ito T, Nakamori S, Ishii H, Kodama Y, Morizane C, Okusaka T, Yanagimoto H, Notohara K, Taguchi H, Kitano M, Yane K, Maguchi H, Tsuchiya Y, Komoto I, Tanaka H, Tsuji A, Hashigo S, Kawaguchi Y, Mine T, Kanno A, Murohisa G, Miyabe K, Takagi T, Matayoshi N, Yoshida T, Hara K, Imamura M, Furuse J, Yatabe Y, Mizuno N.
Rb Loss and KRAS Mutation Are Predictors of the Response to Platinum-Based Chemotherapy in Pancreatic Neuroendocrine Neoplasm with Grade 3: A Japanese Multicenter Pancreatic NEN-G3 Study.
Clin Cancer Res. 2017 Aug 15;23(16):4625-4632.
17. Yoshioka M, Ohashi S, Ida T, Nakai Y, Kikuchi O, Amanuma Y, Matsubara J, Yamada A, Miyamoto S, Natsuizaka M, Nakagawa H, Chiba T, Seno H, Muto M.
Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells.
J Exp Clin Cancer Res. 2017 Aug 1;36(1):101.
18. Dang H, Takai A, Forgues M, Pomyen Y, Mou H, Xue W, Ray D, Ha KCH, Morris QD, Hughes TR, Wang XW.
Oncogenic Activation of the RNA Binding Protein NELFE and MYC Signaling in Hepatocellular Carcinoma.
Cancer Cell. 2017 Jul 10;32(1):101-114.
19. Goto N, Ueo T, Fukuda A, Kawada K, Sakai Y, Miyoshi H, Taketo MM, Chiba T, Seno H.
Distinct roles of Hes1 in normal stem cells and tumor stem-like cells of the intestine.
Cancer Res. 2017 Jul 1;77(13):3442-3454.
20. Kou T, Kanai M, Yamamoto Y, Kamada M, Nakatsui M, Sakuma T, Mochizuki H, Hiroshima A, Sugiyama A, Nakamura E, Miyake H, Minamiguchi S, Takaori K, Matsumoto S, Haga H, Seno H, Kosugi S, Okuno Y, Muto M.
Clinical Sequencing Using a Next-Generation Sequencing-Based Multiplex Gene Assay in Patients with Advanced Solid Tumors.
Cancer Sci. 2017 Jul;108(7):1440-1446.
21. Ogawa S, Imai Y, Inokuma T.
Mimicking Gastric Natural Killer/T-Cell Lymphoma.
Gastroenterology. 2017 Jul;153(1):e22-e23.
22. Elmaghloub R, Elbahrawy A, Didamony GE, Elwassief A, Saied Mohammad AG, Alashker A, Zedan H, Abdallah AM, Hemidah MH, Elmestikawy A, Fayoumei ME, Shahba H, Gawish A, Morsy MH, Hashim A, Abdelbaseer MA, Ueda Y, Chiba T, Abdelhafeez H.
Hepatitis B Virus Genotype E Infection among Egyptian Health Care Workers.
J Transl Int Med. 2017 Jun 30;5(2):100-105.
23. Kuwada T, Shiokawa M, Uza N, Kodama Y.
A case of cystic type intraductal papillary neoplasm of the bile duct diagnosed by SpyGlass DS, a novel peroral cholangioscopy.
Arab J Gastroenterol. 2017 Jun;18(2):118-119.
24. Aoyama I, Ohashi S, Amanuma Y, Hirohashi K, Mizumoto A, Funakoshi M, Tsurumaki M, Nakai Y, Tanaka K, Hanada M, Uesaka A, Chiba T, Muto M.
Establishment of a Quick and Highly Accurate Breath Test for ALDH2 Genotyping.
Clin Transl Gastroenterol. 2017 Jun 8;8(6):e96.
25. Nishikawa Y, Kanai M, Narahara M, Tamon A, Brown JB, Taneishi K, Nakatsui M, Okamoto K, Uneno Y, Yamaguchi D, Tomono T, Mori Y, Matsumoto S, Okuno Y, Muto M.
Association between UGT1A1*28*28 genotype and lung cancer in the Japanese population.
Int J Clin Oncol. 2017 Apr;22(2):269-273.
26. Nishikawa Y, Funakoshi T, Horimatsu T, Miyamoto S, Matsubara T, Yanagita M, Nakagawa S, Yonezawa A, Matsubara K, Muto M.
Accumulation of alpha-fluoro-beta-alanine and fluoro mono acetate in a patient with 5-fluorouracil-associated hyperammonemia.
Cancer Chemother Pharmacol. 2017 Mar;79(3):629-633.
27. Nakayama Y, Fukuda A, Kodama Y.
A Tumor Localized in the Portal Vein.
Gastroenterology. 2017 Apr;152(5):e7-e9.
28. Furuhata A, Minamiguchi S, Shirahase H, Kodama Y, Adachi S, Sakurai T, Haga H.
Immunohistochemical Antibody Panel for the Differential Diagnosis of Pancreatic Ductal Carcinoma From Gastrointestinal Contamination and Benign Pancreatic Duct Epithelium in Endoscopic Ultrasound-Guided Fine-Needle Aspiration.
Pancreas. 2017 Apr;46(4):531-538.
29. Yoshizato T, Nannya Y, Atsuta Y, Shiozawa Y, Iijima-Yamashita Y, Yoshida K, Shiraishi Y, Suzuki H, Nagata Y, Sato Y, Kakiuchi N, Matsuo K, Onizuka M, Kataoka K, Chiba K, Tanaka H, Ueno H, Nakagawa MM, Przychodzen B, Haferlach C, Kern W, Aoki K, Itonaga H, Kanda Y, Sekeres MA, Maciejewski JP, Haferlach T, Miyazaki Y, Horibe K, Sanada M, Miyano S, Makishima H, Ogawa S.
Genetic abnormalities in myelodysplasia and secondary acute myeloid leukemia: impact on outcome of stem cell transplantation.
Blood. 2017 Apr 27;129(17):2347-2358.
30. Kato M, Ishimaru S, Seki M, Yoshida K, Shiraishi Y, Chiba K, Kakiuchi N, Sato Y, Ueno H, Tanaka H, Inukai T, Tomizawa D, Hasegawa D, Osumi T, Arakawa Y, Aoki T, Okuya M, Kaizu K, Kato K, Taneyama Y, Goto H, Taki T, Takagi M, Sanada M, Koh K, Takita J, Miyano S, Ogawa S, Ohara A, Tsuchida M, Manabe A.
Long-term outcome of 6-month maintenance chemotherapy for acute lymphoblastic leukemia in children.
Leukemia. 2017 Mar;31(3):580-584.
31. Takeda H, Ueda Y, Inuzuka T, Yamashita Y, Osaki Y, Nasu A, Umeda M, Takemura R, Seno H, Sekine A, Marusawa H.
Evolution of multi-drug resistant HCV clones from pre-existing resistant-associated variants during direct-acting antiviral therapy determined by third-generation sequencing.
Sci Rep. 2017 Mar 31;7:45605.
32. Matsumoto T, Takahashi K, Inuzuka T, Kim S, Kurosaki T, Kawakami S, Chiba T, Seno H, Marusawa H.
Activation of TNF-alpha-AID axis and co-inhibitory signals in coordination with Th1-type immunity in a mouse model recapitulating hepatitis B.
Antiviral Res. 2017 Mar;139:138-145.
33. Kimura Y, Ikuta K, Kimura T, Chiba T, Oshima H, Oshima M, Nishi E, Seno H.
Nardilysin regulates inflammation, metaplasia, and tumors in murine stomach.
Sci Rep. 2017 Feb 23;7:43052.
34. Basak O, Beumer J, Wiebrands K, Seno H, van Oudenaarden A, Clevers H.
Induced Quiescence of Lgr5+ Stem Cells in Intestinal Organoids Enables Differentiation of Hormone-Producing Enteroendocrine Cells.
Cell Stem Cell. 2017 Feb 2;20(2):177-190.e4.
35. Sakuma Y, Kodama Y, Sogabe Y, Nakai Y, Yamashita Y, Mikami S, Kajimura K, Ikeda K, Tamaki H, Iwamoto S, Matsuda F, Fujita K, Uza N, Kawamura T, Uemoto S, Seno H, Chiba T, Yazumi S; Kyoto Pancreatobiliary Study Group.
Diagnostic performance of a new “endoscopic scraper” for malignant biliary strictures: A multicenter prospective study.
Gastrointest Endosc. 2017 Feb;85(2):371-379.
36. Matsubayashi H, Takaori K, Morizane C, Maguchi H, Mizuma M, Takahashi H, Wada K, Hosoi H, Yachida S, Suzuki M, Usui R, Furukawa T, Furuse J, Sato T, Ueno M, Kiyozumi Y, Hijioka S, Mizuno N, Terashima T, Mizumoto M, Kodama Y, Torishima M, Kawaguchi T, Ashida R, Kitano M, Hanada K, Furukawa M, Kawabe K, Majima Y, Shimosegawa T.
Familial pancreatic cancer: Concept, management and issues.
World J Gastroenterol. 2017 Feb 14;23(6):935-948.
37. Takeda H, Takai A, Inuzuka T, Marusawa H.
Genetic basis of hepatitis virus-associated hepatocellular carcinoma: linkage between infection, inflammation, and tumorigenesis.
J Gastroenterol. 2017 Jan;52(1):26-38.
38. Shimizu T, Chiba T, Marusawa H.
Helicobacter pylori-Mediated Genetic Instability and Gastric Carcinogenesis.
Curr Top Microbiol Immunol. 2017;400:305-323.
39. Ogawa S, Ishii T, Minaga K, Nakatani Y, Hatamaru K, Akamatsu T, Seta T, Urai S, Uenoyama Y, Yamashita Y, Kudo M.
The Feasibility of 18-mm-Diameter Colonic Stents for Obstructive Colorectal Cancers.
Oncology. 2017;93 Suppl 1:43-48.


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